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Year : 2020  |  Volume : 6  |  Issue : 2  |  Page : 171-174

Acute fatty liver of pregnancy: A clinical dilemma

1 Department of Obstetrics and Gynaecology, AIIMS, Nagpur, Maharashtra, India
2 Department of Obstetrics and Gynaecology, AIIMS, Jodhpur, Rajasthan, India
3 Department of Obstetrics and Gynaecology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra, India
4 Department of Medicine, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, India

Correspondence Address:
Dr. Charu Sharma
Department of Obstetrics and Gynaecology, AIIMS, Jodhpur, Rajasthan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJCFM.IJCFM_22_20

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Acute Fatty Liver of Pregnancy (AFLP) is a rare and life-threatening obstetric emergency. Although the exact pathogenesis is unknown, the cases of AFLP are believed to be associated with abnormal fatty acid oxidation. The diagnosis of AFLP is a challenging task for the clinicians because of the nonspecific clinical presentation which may mimic conditions such as acute viral hepatitis, preeclampsia or Hemolysis, Elevated Liver Enzymes, and Low Platelet Count (HELLP) syndrome. Early diagnosis, prompt obstetric management, intensive supportive care, and a multidisciplinary approach are the key to a good outcome. We here present two similar cases of AFLP with two different outcomes managed in a tertiary care center of the Andaman and Nicobar Islands.

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